SGC-SMARCA-BRDVIII Datasheet DC Chemicals

Description	SGC-SMARCA-BRDVIII is a potent and selective SMARCA2/4 BRD inhibitor.
Cat.No	DC48075
Name	SGC-SMARCA-BRDVIII

Chemical Properties

CAS	1997319-84-2
Formula	C19H25N5O3
MW	371.43
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Wanior M, et, al. Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J Med Chem. 2020 Dec 10;63(23):14680-14699. [2]. Mélin L, et, al. Design and Synthesis of LM146, a Potent Inhibitor of PB1 with an Improved Selectivity Profile over SMARCA2. ACS Omega. 2021 Aug 9;6(33):21327-21338.

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