SGC2085 Hydrochloride Datasheet DC Chemicals

Description	SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.
Cat.No	DC43161
Name	SGC2085 Hydrochloride

Chemical Properties

CAS	1821908-49-9
Formula	C19H25CLN2O2
MW	348.87
Storage	0°C (short term), -20°C (long term), desiccated

References

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