Si5-N14 Datasheet DC Chemicals

Description	Si5-N14 is a siloxane-incorporated lipid for lung-targeting mRNA delivery. The siloxane moieties enhance cellular internalization of mRNA-LNPs and improve their endosomal escape capacity, augmenting their mRNA delivery efficacy.
Cat.No	DC60663
Name	Si5-N14

Chemical Properties

CAS	3006860-57-4
Formula	C36H71NO3SI
MW	594.528
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery-Michael J. Mitchell -Nature Nanotechnology (2024)

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