Description
Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells.
Cat.No
A749
Name
Siplizumab
Chemical Properties
CAS
288392-69-8
Synonyms
Immunoglobulin G1,anti-(human CD2 (antigen)) (human-rat monoclonal MEDI-507 g1-chain), disulfide withhuman-rat monoclonal MEDI-507 light chain, dimer;Immunoglobulin G1,anti-(human CD2 (antigen)) (human-rat monoclonal MEDI-507 g1-chain), disulfide withhuman-rat monoclonal MED;MEDI507;Siplizumab;Medi507;Medi-507;Research Grade Siplizumab
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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