Siramesine free base Datasheet DC Chemicals
Description Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress.
Cat.No DC75550
Name Siramesine free base

Chemical Properties

CAS 147817-50-3
Formula C30H31FN2O
MW 454.59
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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