SKF-86002 dihydrochloride Datasheet DC Chemicals
Description SKF-86002 dihydrochloride is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 dihydrochloride inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 dihydrochloride inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.
Cat.No DC46923
Name SKF-86002 dihydrochloride

Chemical Properties

CAS 116339-68-5
Formula C16H14CL2FN3S
MW 370.27
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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