Sofpironium bromide Datasheet DC Chemicals
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Cat.No DC45324
Name Sofpironium bromide

Chemical Properties

CAS 1628106-94-4
Formula C22H32BRNO5
MW 470.397186279297
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：1628106-94-4
Product Name：Sofpironium bromide
Synonyms：Sofpironium bromide;Sofpironium bromide [USAN];Sofpironium bromide (JAN/USAN/INN);D10989;Q27268000;(3R)-3-((R)-2-Cyclopentyl-2-hydroxy-2-phenylacetoxy)-1-(2-ethoxy-2-oxoethyl)-1-methylpyrrolidin-1-ium bromide;Pyrrolidinium, 3-(((2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy)-1-(2-ethoxy-2-oxoethyl)-1-methyl-, bromide (1:1), (3R)-
EINEC:
Molecular Formula：C22H32BRNO5
Molecular Weight：470.397186279297
Target:
In Vivo Sofpironium bromide exhibits anticholinergic activity by inhibiting the contractile activity of guinea pig ileal tissue in a concentration-dependent manner. In a rat model, Sofpironium bromide reduces footpad sweating induced by Pilocarpine (a muscarinic receptor agonist)[1].
In Vitro Sofpironium bromide is metabolized mainly through non-enzymatic hydrolysis, and also through oxidative metabolism via CYP2D6 and CYP3A4[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Julia Paik, et al. Sofpironium Bromide: First Approval. Drugs. 2020 Dec;80(18):1981-1986.
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