SPR519 Datasheet DC Chemicals

Description	SPR519 is a potent dual inhibitor of PI3Kα and mTOR kinases with IC50 (PI3Kalpha) = 30 nM and IC50 (mTOR) = 10 nM. SPR519 exhibits an EC50 of low sub-micromolar range among various tested cancer cell lines such as A2780 (0.23 μM), PC3 (0.48 μM), and SKOV3 (0.50 μM).
Cat.No	DC65299
Name	SPR519

Chemical Properties

CAS	1391923-59-3
Formula	C19H21N7O3S
MW	427.480141401291
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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