SS47 Datasheet DC Chemicals
Description SS47, a PROTAC-based HPK1 degrader, exerts proteasome-mediated HPK1 degradation. The degradation of HPK1 via SS47 also significantly enhances the in vivo antitumor efficacy of BCMA CAR-T cell treatment. HPK1, an immunosuppressive regulatory kinase, is a promising target for cancer immunotherapies.
Cat.No DC71629
Name SS47

Chemical Properties

CAS 2636072-62-1
Formula C49H56N6O12S
MW 953.07
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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