TAK-020 Datasheet DC Chemicals

Description	TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate.
Cat.No	DC47717
Name	TAK-020

Chemical Properties

CAS	1627603-21-7
Formula	C18H17N5O3
MW	351.359283208847
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Sabat M, et al. Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design. J Med Chem. 2021 Sep 9;64(17):12893-12902.

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