TH35 Datasheet DC Chemicals
Description TH35 is a novel class of CRBN-recruiting cGAS-targeting PROTAC degrader with IC50 of 1.8 and 4.8 μM,in THP1-Lucia ISG and RAW-Lucia ISG cells, respectively. TH35 exhibits strong anti-inflammatory effects in the DSS-induced UC mice model.
Cat.No DC60815
Name TH35

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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