Thalidomide-d4 Datasheet DC Chemicals

Description	Thalidomide-d4 is a deuterium-enriched analog of the prototypic immunomodulatory drug thalidomide, featuring four strategically positioned deuterium substitutions. This isotopically labeled compound retains the parent molecule's ability to bind cereblon (CRBN) with high affinity (Kd ≈ 250 nM), thereby modulating the activity of the CUL4-RBX1-DDB1-CRBN E3 ubiquitin ligase complex.
Cat.No	DC67348
Name	Thalidomide-d4

Chemical Properties

CAS	1219177-18-0
Formula	C13H6D4N2O4
MW	262.2541
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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