THK-5117 Datasheet DC Chemicals
Description THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe.
Cat.No DC70979
Name THK-5117

Chemical Properties

CAS 1374107-54-6
Formula C19H19FN2O2
MW 326.36
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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