TLR7/8 antagonist 2 Datasheet DC Chemicals

Description	TLR7/8 antagonist 2 (Compound 15) is a potent and orally active agonist of TLR7/8 with IC50s of 4.9 and 0.6 nM, respectively. Inappropriate activation of TLR7 and TLR8 is linked to several autoimmune diseases, such as lupus erythematosus. TLR7/8 antagonist 2 has the potential for the research of autoimmune diseases.
Cat.No	DC49678
Name	TLR7/8 antagonist 2

Chemical Properties

CAS
Formula	C22H26FN5
MW	379.47
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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