TP0586532 Datasheet DC Chemicals
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Cat.No DC46373
Name TP0586532

Chemical Properties

CAS 2427584-96-9
Formula C26H28N4O4
MW 460.52
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target: IC50: 0.101 μM (non-hydroxamate LpxC)[1]
In Vivo
In Vitro TP0586532 as a compound with a low cardiovascular risk that is effective against K. pneumoniae, including resistant strains[1].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.
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