TPX-0022(CSF1R-IN-2) Datasheet DC Chemicals

Description	TPX-0022 (CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.
Cat.No	DC46183
Name	TPX-0022(CSF1R-IN-2)

Chemical Properties

CAS	2271119-26-5
Formula	C20H20FN7O2
MW	409.425
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. WO 2019023417 A1.

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