TPX-0131 Datasheet DC Chemicals

Description	TPX-0131 is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK (IC50 of 1.4 nM) and ALK-resistant mutation, e.g. G1202R (IC50 of 0.3 nM), L1196M (IC50 of 0.3 nM). TPX-0131 has strong antitumor activities.
Cat.No	DC45792
Name	TPX-0131

Chemical Properties

CAS	2648641-36-3
Formula	C21H20F3N5O3
MW	447.41
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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