UAMC-1110 Datasheet DC Chemicals

Description	SP-13786(UAMC-1110) is a Novel potent and selective inhibitor of fibroblast activation protein (FAP), displaying low nanomolar inhibitory potency and high selectivity against the related dipeptidyl peptidases (DPPs) DPPIV, DPP9, DPPII, and prolyl oligopeptidase (PREP)
Cat.No	DC42729
Name	UAMC-1110

Chemical Properties

CAS	1448440-52-5
Formula	C17H14F2N4O2
MW	344.32
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Jansen K, et al. Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP). J Med Chem. 2014 Apr 10;57(7):3053-74.

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