UNC3133 Datasheet DC Chemicals

Description	UNC3133 (Compound 16) is a selective and orally active macrocyclic mer tyrosine kinase (MerTK) inhibitor with an IC50 of 8.1 nM. UNC3133 has certain selectivity towards the TAM family (Axl and Tyro3) (with a selectivity of approximately 7 times for Axl and about 10 times for Tyro3), and has similar inhibitory activity towards Flt3. UNC3133 exhibits anti-tumor and anti-infection activities.
Cat.No	DC79744
Name	UNC3133

Chemical Properties

CAS	2011034-35-6
Formula	C30H44N6O
MW	504.71
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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