VU0606170 Datasheet DC Chemicals

Description	VU 0606170 is a selective sodium-activated potassium channel KNa1.1 (Slack, Slo2.2) inhibitor with EC50 of 1.84 and 1.16 uM for WT Slack and A934T Slack, repectively.VU0606170 did not modulate HEK293 channels expressing Slick, Slo1 α1/β1, Slo1 α1/β2, Slo1 α1/β3, Slo1 α1/β4, or Slo3 channels. also potently inhibits G288S and R428Q Slack channels.VU0606170 also proved effective at significantly decreasing the firing rate in overexcited, spontaneously firing cortical neuron cultures.
Cat.No	DC70890
Name	VU0606170

Chemical Properties

CAS	879054-55-4
Formula	C19H29CLN4O4S
MW	444.975
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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