VX-803 (M4344) Datasheet DC Chemicals

Description	VX-803 (M4344) is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity.
Cat.No	DC39113
Name	VX-803 (M4344)

Chemical Properties

CAS	1613191-99-3
Formula	C25H29F2N9O3
MW	541.55
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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