XEN 602 Datasheet DC Chemicals
Description XEN-602 represents a breakthrough in DMT1 pharmacology as a picomolar-range inhibitor of divalent metal transporter 1 (SLC11A2), demonstrating unprecedented selectivity for manganese transport blockade (IC₅₀ = 300 pM in HEK293 cells). This structurally optimized small molecule achieves complete suppression of DMT1-mediated Mn²⁺ uptake while maintaining exceptional target specificity, as evidenced by minimal interference with other metal transporters. Its unmatched potency enables precise interrogation of DMT1's physiological roles and therapeutic exploration for manganese dysregulation disorders.
Cat.No DC74222
Name XEN 602

Chemical Properties

CAS
Formula C45H51FN10O2S4
MW 911.21
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Return Policy
If you are in any way unsatisfied with your purchase, you may return any item(s) within 365 days of its original purchase date.
Please provide your Order Number in the email. We strive to reply to all email inquiries within one business day.
Tel: +86-21-58447131
Fax: +86-21-61642470

Email:
sales@dcchemicals.com
order@dcchemicals.com

Website:
www.dcchemicals.com