YN14 (mixture of diastereomers) Datasheet DC Chemicals

Description	YN14 mixture of diastereomers is the diastereomers of YN14). YN14 is a KRASG12C proteolysis targeting chimera (PROTAC). YN14 is highly potent and selective KRASG12C degrader and induces a stable KRASG12C: YN14: VHL ternary complex with low binding free energy (ΔG). YN14 has antiproliferative effects and significantly inhibits KRASG12C-mutant cancer cell growth.
Cat.No	DC79566
Name	YN14 (mixture of diastereomers)

Chemical Properties

CAS	3053689-54-3
Formula	C62H75F2N11O7S
MW	1156.39
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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