Zeteletinib hemiadipate Datasheet DC Chemicals

Description	Zeteletinib (BOS-172738; DS-5010) hemiadipate is an orally active, selective RET kinase inhibitor with nanomolar potency against RET and >300-fold selectivity against VEGFR2. Zeteletinib hemiadipate shows exquisite potency for the wild type RET, RETV804M/L gatekeeper mutants, and the most common oncogenic RET mutation M918T. Zeteletinib hemiadipate has potent antitumor activity.
Cat.No	DC47868
Name	Zeteletinib hemiadipate

Chemical Properties

CAS	2375837-06-0
Formula	C25H23F3N4O4.1/2C6H10O4
MW	573.55
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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