Cat. No. | Product name | CAS No. |
DC73493 |
TG11-77
TG11-77 is a potent, selective, brain-permeable and orally available antagonist of the prostaglandin E2 (PGE2) receptor subtype EP2 with KB value of 9.7 nM. |
2550393-38-7 |
DC73495 |
1-Piperidine Propionic Acid
1-Piperidine Propionic Acid (1-PPA) is an allosteric Inhibitor of protease activated receptor-2 (PAR2) with IC50 of 2.3 uM. |
26371-07-3 |
DC73496 |
NRD-21
NRD-21 is a potent, selective, reversible, negative allosteric modulator of PAR1 with IC50 of 0.37 uM in calcium mobilization assays. |
2403529-11-1 |
DC73497 |
TFLLRN-NH2
TFLLRN-NH2 is a potent, PAR1-selective agonist peptide with EC50 of 1.9 uM. |
197794-83-5 |
DC73498 |
Ogremorphin
Ogremorphin (OGM, OGM8345) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.71 uM. |
294648-66-1 |
DC73499 |
Ogremorphin-1
Ogremorphin-1 (OGM1) is a highly specific, first-in-class small-molecule inhibitor of GPR68 with IC50 of 0.16 uM. |
352563-21-4 |
DC73500 |
DC591053
DC591053 (DC 591053) is a selective small molecule agonist of relaxin family peptide receptor 4 (RXFP4) with pEC50 of 7.24 and pKi of 6.95, shows no activity against RXFP3. |
|
DC73501 |
AZ-66
AZ-66 is a highly potent S1R/S2R antagonist with Ki of 0.31/1.76 nM, respectively. |
1259949-59-1 |
DC73502 |
CM-304
CM-304 is a potent, selective sigma-1 receptor (S1R) antagonist with Ki of 3.41 nM, 100-fold selective over S2R. |
1350296-21-7 |
DC73503 |
GM310
GM310 is a small molecule inhibitor of glycolysis, proteotoxicity, inflammation, and impairments in animal models of Alzheime's, Huntington's, and stroke by activation of the Sigma-1 receptor. |
2770374-87-1 |
DC73504 |
JR1-157
Featured
JR1-157 is a potent selective sigma 2 receptor (σ2R) ligand with Ki value of 47 nM, >10-fold selectivity over σ1R. |
2446964-31-2 |
DC73505 |
MAM03055A
MAM03055A is a novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity, exhibits high affinity and strong preference for sigma-2 receptor with Ki of 55.9 nM. |
|
DC73506 |
RC-752
RC-752 is a potent, seletive sigma-1 receptor (S1R) antagonist with Ki of 6.2 nM, 50-fold selective over S2R, shows antinociceptive activity. |
1808994-61-7 |
DC73507 |
WLB-89462
Featured
WLB-89462 (WLB89462) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 13 nM, >100-fold selective over σ1R (Ki=1777 nM). |
2849471-75-4 |
DC73508 |
CRN02481
CRN02481 is a potent and selective SST5 receptor agonist with EC50 of 0.37 nM (human SST5), with excellent selectivity against SST1, SST2, SST3 and SST4 receptors. |
2374259-11-5 |
DC73509 |
S6821
S6821 (S 6821) is a potent and selective bitter taste receptor TAS2R8 with IC50 of 21 nM. |
1119831-25-2 |
DC73510 |
Org 274179-0
Featured
Org 274179-0 is a highly potent, allosteric antagonist of the thyroid-stimulating hormone receptor (TSH receptor), inhibits bTSH-, hTSH- and M22-mediated CRE-luciferase transactivation in the CHO cell line. |
1421683-12-6 |
DC73511 |
SYD5115
(SYD-5115, SYD 5115)
SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively. |
|
DC73512 |
OPC-61815
OPC-61815 is a water-soluble phosphate ester pro-drug of Tolvaptan (Cat# PC-45125), which is an orally active vasopressin V2 receptor antagonist. |
942619-79-6 |
DC73513 |
RGH-122
RGH-122 is a potent, selective, and orally bioavailable V1a receptor antagonist with Ki/IC50 of 0.3/0.9 nM (hV1a) respectively, >100-fold selectiive over V2 receptor. |
2355304-05-9 |
DC74590 |
Protokylol hydrochloride
Protokylol hydrochloride(Caytine hydrochloride, JB-251 hydrochloride) is a salt form of protokylol and is an agonist of β-adrenergic receptor. Protokylol hydrochloride is also used as a bronchodilator. |
136-69-6 |
DC74598 |
Fasoracetam (NS 105)
Fasoracetam (NS 105) is a metabotropic glutamate receptor activator with a potential to treat vascular dementia. |
110958-19-5 |