Cat. No. | Product name | CAS No. |
DC73898 |
AGI-25696
Featured
AGI-25696 (AGI 25696) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A, blocks the growth of MTAP-deleted tumors in vivo. |
2201066-35-3 |
DC73899 |
AK-3280
AK-3280 (AK 3280, GDC 3280, RG 6069) is an orally available, potential novel anti-fibrotic small molecule under investigation for the treatment of interstitial lung diseases. |
1799412-33-1 |
DC73900 |
AKST1220
AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory. |
1400796-48-6 |
DC73901 |
Alrefimotide
Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen). |
|
DC73902 |
AM9053
(AM 9053)
AM9053 (AM 9053) is a potent, selective inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 30 nM, with limited effect on FAAH activity (IC50>100 uM). |
157469-21-1 |
DC73903 |
Antabactin
Antabactin (ANT) is a highly potent pan-abscisic acid (ABA) receptor antagonist with EC50 of 760 nM and picomolar dissociation constant, disrupts signaling by preventing receptor-PP2C interactions. |
2570821-88-2 |
DC73904 |
AP736
AP736 is a damantyl benzylbenzamide derivative with anti-melanogenic effects in melanocytes in vitro, acts via the downregulation of tyrosinase, TRP-1 and MITF expression. |
1365531-21-0 |
DC73905 |
APC655
APC655 is a potent activator of protein folding and unfolded protein response (UPR) modulator, APC655 activates ATF6 pathway and chaperone expression. |
385786-31-2 |
DC73906 |
AQIM-I
AQIM-I is a highly potent small molecule survivin inhibitor by targeting ILF3/NF110, binds to ILF3/NF110 with KD value of 163 nM in SPR assays, has broad-spectrum antitumor activity. |
2247881-73-6 |
DC73907 |
ARL67156
ARL67156 (FPL 67156) is a selective inhibitor of ecto-ATPase, ARL67156 is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. |
160928-38-1 |
DC73908 |
ART899
ART899 (ART-899) is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM, shows with improved in vivo stability compared to ART558. |
2607139-85-3 |
DC73909 |
ARUK2001607
(ARUK 2001607)
ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
2924824-56-4 |
DC73910 |
ARUK200282
ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
|
DC73911 |
ARUK2002821
ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
|
DC73912 |
ARUK2007145
ARUK2007145 is a potent, selective and cell-active PI5P4Kα/γ dual inhibitor with pIC50 of 7.3/8.1, resepctively, shows no activity against PI5P4Kβ. |
|
DC73913 |
ASB17061
ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
1312993-33-1 |
DC73914 |
ASN 90
ASN90 is a potent, selective, substrate-competitive O-GlcNAcase (OGA) inhibitor with IC50 of 10.2 nM. |
1884154-02-2 |
DC73915 |
ASP7967
ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM. |
1246834-49-0 |
DC73916 |
AZ13792138
AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
|
DC73917 |
BCL3ANT
BCL3ANT (NSC-659509) is a small molecule inhibitor of Bcl-3-mediated cyclin D1 expression, reduces cyclin D1 luciferase activity in Bcl-3-overexpressing melanoma cells with IC50 of 40.4 uM. |
910855-84-4 |
DC73918 |
BD442618
BD442618 (BD 442618) is a potent small-molecule GPR52 agonist. |
|
DC73919 |
BD50265
BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |