Moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (MAO) inhibitors.

QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18[1][2][3].

Uramustine (INN), also known as uracil mustard, is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.For the detailed information of Uramustine, the solubility of Uramustine in water, the solubility of Uramustine in DMSO, the solubility of Uramustine in PBS buffer, the animal experiment (test) of Uramustine, the cell expriment (test) of Uramustine, the in vivo, in vitro and clinical trial test of Uramustine, the EC50, IC50,and Affinity of Uramustine, Please contact DC Chemicals..

(-) BI97D6 (BI112D1) is a potent, pan-active inhibitor of Bcl-2 family proteins with IC50 of 76, 31, 25, and 122 nM for Bcl-xL, Bcl-2, Mcl-1, and Bfl-1, respectively.

(-)-CXL017 is a small molecule that has selective cytotoxicity toward MDR cancer cell lines in vitro, through inhibition of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) with IC50 of 13.5 uM.

(-)-Eburnamonine is a vasodilator that also acts as a cerebral metabolic stimulant.

(+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. (+)-Kavain is shown to bind at the α4β2δ GABA

(+)-Muscarine is an agonist of muscarinic acetylcholine receptors that was originally found in A. muscaria.

(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.

(+)-Praeruptorin A is a coumarin derivative originally isolated from P. praeruptorum.

(1,5-dimethylhexyl)ammonium chloride is used as a systemic acidifying agent in treatment of severe metabolic alkalosis, in oral acid loading test to diagnose distal renal tubular acidosis, to maintain the urine at an acid pH in the treatment of some urina

(20R)-Protopanaxdiol has protective effect on myocardial ischemia, which may be related to improving free radicals metabolism and myocardial metabolism, decreasing plasma TXA 2 levels.

(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin; apoptosis inducer.

(3-Carboxypropyl)trimethylammonium chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.

(5Z)-7-Oxozeaenol is a potent and selective TAK1 inhibitor with IC50 of 8 nM, displays >33-fold and >62-fold selectivity over MEKK1 and MEKK4 respectively.

(E)-[6]-Dehydroparadol, extracted from patent US 9272994, compound M15, shows growth inhibition and induction of apoptosis against human cancer cells with IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively.

(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid is a constrained Phe analogue which can fold into a beta-bend and a helical structure, and to adopt a preferred side-chain disposition in the peptide.

(R)-9bMS is a potent and selective ACK1 (TNK2) inhibitor with IC50 of 48 nM.

(R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2..

(R)-DNMDP (DNMDP R-form) is the R-form of is DNMDP, which is a potent and selective cancer cell cytotoxic agent that binds to PDE3A, promotes an interaction between PDE3A and Schlafen 12 (SLFN12)..

(R)-GNE-140 (GNE-140) is a novel potent, selective lactate dehydrogenase (LDH) inhibitor with IC50 of 3, 5, and 5 nM for LDHA, LDHB, and LDHC, respectively.

(R)-HZ05 is a potent DHODH inhibitor with IC50 of 11 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo..