| DC21513 |
7DG |
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR) that directly interact with the C-terminal of PKR. |
|
| DC10855 |
7-Epi 10-Desacetyl Paclitaxel
Featured
|
7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells. |
|
| DC10856 |
7-Epipaclitaxel
Featured
|
7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule. |
|
| DC8388 |
8-Bromo-cAMP
Featured
|
8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator. |
|
| DC26033 |
8-Hydroxy-efavirenz
Featured
|
8-Hydroxy-efavirenz is the primary metabolite of the antiretroviral drug Efavirenz, stimulates the glycolytic flux in cultured rat astrocytes. |
|
| DC10186 |
8-O-Acetyl shanzhiside methyl ester |
8-O-Acetyl shanzhiside methyl ester (ND01) is an iridoid glucoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. |
|
| DC20669 |
Imexon |
A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma. |
|
| DC23303 |
A 385358 |
A 385358 is a potent, selective, cell-permeable Bcl-XL inhibitor with Ki of 0.8 nM, displays >80-fold selectivity over Bcl-2 (Ki=64 nM). |
|
| DC24006 |
Nucleoside-Analog-2 |
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
|
| DC24009 |
Nucleoside-Analog-1 |
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
|
| DC9628 |
A 419259 (trihydrochloride)
Featured
|
A 419259 3Hcl is an apoptosis inducing agent that inhibits Src family kinases (c-Src). |
|
| DC22355 |
Lisinopril |
A angiotensin-converting enzyme (ACE) inhibitor for treatment of hypertension, heart failure, and after heart attacks.. |
|
| DC22846 |
NSC-34931 |
A anti-HIV-1 compound that interferes with HIV-I integrase binding to viral DNA.. |
|
| DC22455 |
Ro5-3335 |
A benzodiazepine inhibitor that directly interacts with RUNX1 and CBFβ, represses RUNX1/CBFβ-dependent transactivation in reporter assays. |
|
| DC22605 |
Benzophenonetetracarboxylic acid |
A benzophenone tetracarboxylic derivative that can improve the activity and stability of alkaline phosphatases from psychrophilic and mesophilic organisms.. |
|
| DC20526 |
r(GGGGCC)n binder 1a |
A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM. |
|
| DC25030 |
Migrastatin |
A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration. |
|
| DC21819 |
WP760 |
A bis-anthracycline and melanoma selective agent that demonstrates anti-melanoma activity at low nanomolar concentrations. |
|
| DC22873 |
TM2 115
Featured
|
A BIX-01294 derivative that inhibit malaria parasite histone methyltransferases, resulting in rapid and irreversible parasite death. |
|
| DC7537 |
B-Raf inhibitor (BenzaMide) |
A B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases. |
|
| DC24040 |
AKT inhibitor |
A broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM(biochemical assay), and 0.31 nM (cell function assay). |
|
| DC23922 |
Cercosporamide
Featured
|
A broad-spectrum natural antifungal compound that acts as a selective and highly potent fungal Pkc1 kinase inhibitor. |
|
| DC23987 |
SU14813 maleate |
A broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS. |
|
| DC23920 |
GGTI298 |
A CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
|
| DC22519 |
Norverapamil hydrochloride
Featured
|
Norverapamil HCl is a calcium channel blocker. It is the main active metabolite of verapamil. |
|
| DC24165 |
Aldicarb sulfone |
A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor.. |
|
| DC24166 |
Aldicarb |
A carbamate insecticide that acts as a fast-acting cholinesterase inhibitor.. |
|
| DC22345 |
Penthiopyrad
Featured
|
A carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps. |
|
| DC22369 |
Flumorph |
A carboxylic acid amide (CAA) fungicide.. |
|
| DC22678 |
Acebutolol |
A cardioselective beta blocker for the treatment of hypertension and arrhythmias.. |
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