Cat. No. | Product name | CAS No. |
DC47193 |
OICR-9429-N-C2-NH2
OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs. |
2407457-55-8 |
DC47212 |
Boc-bipiperidine-ethynylbenzoic acid
Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61. |
2308497-81-4 |
DC47213 |
L-Homopropargylglycine hydrochloride
L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor. |
942518-19-6 |
DC47319 |
Dovitinib-RIBOTAC
Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity. |
|
DC47369 |
Propargyl-PEG2-CH2COOH
Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
944561-46-0 |
DC47370 |
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1205744-09-7 |
DC47371 |
1-Bromo-6-chlorohexane
1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs. |
6294-17-3 |
DC47372 |
Bromo-C10-OBn
Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs. |
78277-30-2 |
DC47584 |
PROTAC BRD4 ligand-2
PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718. |
2154358-11-7 |
DC47585 |
PROTAC CDK9 ligand-1
PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs. |
2411021-95-7 |
DC47878 |
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
|
DC47879 |
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
|
DC47884 |
TLR4-IN-C34-C2-COOH
Featured
TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
1159408-54-4 |
DC47885 |
TLR4-IN-C34-C2-amide-C6-OH
TLR4-IN-C34-C2-amide-C6-OH is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis. |
|
DC48040 |
Biotin-PEG8-Vidarabine
Biotin-PEG8-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. |
|
DC48041 |
Biotin-PEG7-C2-S-Vidarabine
Biotin-PEG7-C2-S-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. |
|
DC48042 |
Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. |
|
DC48050 |
ATP-PEG8-Biotin
ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. |
|
DC48369 |
AGB1
Featured
AGB1 is a fast, highly selective, and potent bump-and-hole (B&H)-PROTAC degrader for BromoTag. AGB1 exhibits degradation for Ab:Brd4BD2 L387A and Ab: BromoTag-Brd2 with pDC50s of 7.8 and 7.9. AGB1 exhibits binary affinity to VHL (Kd=125 nM). AGB1 exhibits favorable pharmacokinetic profile in mice with the DC50, 6 h of ∼13 nM. |
2776190-62-4 |
DC48423 |
Boc-NH-PEG11-OH
Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
1556847-53-0 |
DC48429 |
Di(N-succinimidyl) adipate
Di(N-succinimidyl) adipate (DSAP) is an alkyl chain-based PROTAC linker that is applicable to the synthesis of PROTACs. |
59156-70-6 |
DC48432 |
tert-Butyl 11-aminoundecanoate
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker that refers to the PEG composition. tert-Butyl 11-aminoundecanoate is applicable to the synthesis of a series of PROTACs. |
220851-29-6 |