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COA of BLT-1
Description:
BLT-1 is an irreversible Scavenger receptor class B member I (SR-BI) inhibitor that blocks SR-BI-mediated selective lipid uptake and bidirectional cholesterol flux with an IC50 of 50 nM; significantly inhibits baicalin-induced cholesterol efflux in THP-1 macrophages.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | >98% |
| CAS | 321673-30-7 |
| Molecular Weight (MW) | 241.396 |
| Molecular Formula | C12H23N3S |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Reference:
1. Yu M, et al. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12243-8.
2. Nieland TJ, et al. J Lipid Res. 2007 Aug;48(8):1832-45. Epub 2007 May 28.
3. Yu R, et al. Exp Ther Med. 2016 Dec;12(6):4113-4120.