Tetrazine-NHS ester is an NHS activated tetrazine derivative. The chemical stability of tetrazines is lower than methyltetrazines, but it is in acceptable range and thus can be applied for many applications. This reagent was found the fastest kinetics for bioorthogonal reaction with trans-cyclooctene (TCO) as the dienophile.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.