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COA of HG106
Description:
HG106 is a potent SLC7A11 inhibitor and enhances ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | >98% |
| CAS | 928712-10-1 |
| Molecular Weight (MW) | 316.74 |
| Molecular Formula | C15H13ClN4O2 |
| Storage | -20 |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Reference:
Suppression of the SLC7A11/glutathione axis causes synthetic
lethality in KRAS-mutant lung adenocarcinoma
Kewen Hu, … , Mingyao Liu, Xiufeng Pang
J Clin Invest. 2020;130(4):1752-1766. https://doi.org/10.1172/JCI124049.