DC Chemicals-Focus on Bioactive Chemicals

DC Chemicals

-Chemicals for Life Science

-competitive price and high quality!
www.dcchemicals.com

COA of Arcturus lipid 2(ATX-0114)

Description:

Lipid 2,2(8,8) 4C CH3 is an ionizable cationic lipid (pKa = 6.69).1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vivo. LNPs containing lipid 2,2(8,8) 4C CH3 and encapsulating siRNA targeting Factor VII decrease plasma Factor VII protein levels by 90% in mice.

Chemical Information

Catalog Featured products
Purity of current batch >95%
CAS 2230647-30-8
Molecular Weight (MW) 654.50
Molecular Formula C37H70N2O5S
Storage -20

Handling:

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Reference:

Payne, J. E. & Chivukula P. Ionizable Cationic Lipid for RNA Delivery. https://patents.google.com/patent/US9670152B2/en.