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COA of AM-9747
Description:
AM-9747 is an MTA-cooperative PRMT5 inhibitor with IC50 of 9.5 nM in the MTAP-del viability assay and shows outstanding 75-fold selectivity over the corresponding isogenic MTAP-WT cellular viability. AM-9747 also shows a significant oral antitumor effect in mouse models employing PDXs.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | 98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.