DC Chemicals
-Chemicals for Life Science
-competitive price and high quality!www.dcchemicals.com
Description:
Ionizable lipid-2 is a cationic lipid for nucleic acid delivery, with the ability to form lipid nanoparticle mRNA vaccines that exhibit in vitro stability and immunostimulatory activity.This ALC-0315 analogue retains its ionizable tertiary amine, hydroxybutyl headgroup, and dual branched hydrophobic tails, while replacing the two ester linkages with carbonate groups. This modification may alter hydrolytic stability, biodegradability, membrane interactions, and overall LNP delivery performance.
Chemical Information
| Catalog | DC60965 |
|---|---|
| Purity of current batch | 98% |
| CAS | 2763904-72-7 |
| Molecular Weight (MW) | 826.323577165604 |
| Molecular Formula | C50H99NO7 |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.