Description:
GL-4512 is a preclinical small-molecule direct modulator of leukocyte immunoglobulin-like receptor B4 (LILRB4, also known as ILT3/CD85k). It binds to immobilized LILRB4 protein, inhibits the LILRB4–SCG2 interaction, and suppresses LILRB4-mediated immunosuppressive signaling pathways associated with tumor immune evasion.
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.