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COA of QR-6401
Description:
QR-6401 is a highly potent and selective macrocyclic CDK2 inhibitor with IV50 of 0.37 nM. QR-6401 exhibits good selectivity against other closely related kinases, such as CDK1, CDK4, CDK6, CDK9 and GSK3β. QR-6401 demonstrates robust antitumor efficacy in an OVCAR3 ovarian cancer xenograft model via oral administration.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | 98% |
| Molecular Weight (MW) | 369.43 |
| Molecular Formula | C19H23N5O3 |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.