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COA of STC15

Description:

STC-15 is a groundbreaking, orally bioavailable, highly selective inhibitor of METTL3, an RNA methyltransferase enzyme that plays a critical role in regulating gene expression through N6-methyladenosine (m6A) modification of RNA. METTL3 is implicated in the pathogenesis of various cancers, including acute myeloid leukemia (AML) and solid tumors. STC-15 represents the first molecule specifically targeting an RNA methyltransferase enzyme to enter clinical development, marking a significant milestone in the field of epitranscriptomics and cancer therapy.

Chemical Information

Catalog Featured products
Purity of current batch >98%
CAS 2648257-56-9
Molecular Weight (MW) 415.487604856491
Molecular Formula C24H25N5O2
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Handling:

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.