Lenalidomide hydrochloride (CC-5013 hydrochloride), a thalidomide-derived molecular glue, functions as an orally bioavailable immunomodulatory agent. By binding to the ubiquitin E3 ligase cereblon (CRBN), it recruits the CRBN-CRL4 complex to induce selective ubiquitination and degradation of lymphoid transcription factors IKZF1 and IKZF3. This mechanism underlies its potent activity against mature B-cell malignancies, including multiple myeloma, while also stimulating IL-2 secretion from T cells.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.