KT-333 diammonium is a molecular glue degrader that selectively targets STAT3 for proteasomal degradation by bridging interactions between STAT3 and the VHL E3 ubiquitin ligase complex. Exhibiting high specificity for STAT3 degradation, this compound demonstrates potent antitumor efficacy. Its therapeutic potential is particularly relevant in hematologic malignancies, including large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL).

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.