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COA of CP-LC-1074

Description:

CP-LC-1074 is a homocysteine-derived ionizable cationic lipid that enables highly efficient in vivo delivery of various RNA therapeutics (including mRNA, cRNA, and saRNA) with robust protein expression. When formulated in standard LNP compositions (50:38.5:10:1.5 molar ratio of ionizable lipid:cholesterol:DOPE:PEG-lipid), it demonstrates superior lung-specific targeting compared to commercial alternatives following intravenous administration, while maintaining an excellent safety profile.

Chemical Information

Catalog Cationic/Ionizable Lipids
Purity of current batch >98%
Molecular Weight (MW) 1060.7
Molecular Formula C57H109N3O8S3
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Handling:

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.