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COA of FTT5 LLNs
Description:
FTT5 LLNs is a modified TT3-derived lipidoid optimized for nucleic acid delivery via lipid-like nanoparticles (LLNs). These formulations demonstrate hepatic tropism in mice and enhance reporter gene expression in Hep3B cells. Therapeutically, FTT5 LLNs successfully deliver Factor VIII mRNA to restore clotting activity in hemophilic mice and enable in vivo genome editing applications.
Chemical Information
| Catalog | Cationic/Ionizable Lipids |
|---|---|
| Purity of current batch | >98% |
| CAS | 2803606-43-9 |
| Molecular Weight (MW) | 1989.1 |
| Molecular Formula | C120H222N6O15 |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.