Zolucatetide demonstrates potent inhibitory activity against β-catenin, exhibiting sub-50 nanomolar IC50 values in biochemical assays. This investigational compound mechanistically disrupts the protein-protein interaction between β-catenin and T-cell factor (TCF) transcription factors, thereby interfering with canonical Wnt signaling pathway activation. Preclinical studies have revealed its promising antitumor efficacy across multiple cancer models.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.