Description:
MOMA-341 is a highly selective covalent inhibitor targeting the Werner syndrome helicase (WRN) protein. Research has demonstrated that WRN plays an essential role in maintaining tumor cell viability in microsatellite instability-high (MSI-H) cancers, while being dispensable in normal tissues. This unique biological characteristic positions WRN inhibition as a promising therapeutic strategy that could selectively target cancer cells while minimizing effects on healthy tissues.
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.