Description:
AD-5591 (AD5591) is a potent, selective, new generation small molecule ALDH2 activator, has the improved biological activities and pharmacological properties compared to Alda-1.
AD-5591 (100 μM) significantly increases the enzymatic activity of recombinant WT and mutant human ALDH2 proteins.
AD-5591 is the active form of AD-9308.
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.
Reference:
1. Chang YC, et al. Nat Commun. 2023 Sep 25;14(1):5971.