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COA of CPAG-1
Description:
CPAG-1 (PGRMC2 activator CPAG-1) is a small-molecule activator of PGRMC2.
CPAG-1 treatment had no effect on weight or food intake but treated mice had reduced fasting glycemia and insulin levels.
CPAG-1 decreased Rev-Erbα protein in BAT of CPAG-1-treated mice.
CPAG-1 also significantly increased labile heme in the nucleus of brown adipocytes from CPAG-1-treated mice within 4 days of treatment.
Chemical Information
| Catalog | Featured products |
|---|---|
| Purity of current batch | >98% |
| CAS | 2094991-62-3 |
| Molecular Weight (MW) | 326.44 |
| Molecular Formula | C20H26N2O2 |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Reference:
1. Andrea Galmozzi, et al. Nature. 2019 Dec;576(7785):138-142.
2. Christopher G Parker, et al. Cell. 2017 Jan 26;168(3):527-541.e29.