Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis.1,2,3Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. IWP-2 (Item No. 13951) is an inhibitor of Wnt production (IC50 = 27 nM) that inactivates porcupine, a membrane-bound O-acyltransferase whose palmitoylation activity is essential For the signaling ability and secretion of Wnt proteins.4 IWP-2-V2 is a less potent IWP-2 derivative whose chemical structure retains the benzothiazole group of its parent compound.4 It has been used to determine which structural features of IWP-2 are essential For impairing Wnt/β-catenin pathway activity.4For the detailed information of IWP-2-V2, the solubility of IWP-2-V2 in water, the solubility of IWP-2-V2 in DMSO, the solubility of IWP-2-V2 in PBS buffer, the animal experiment (test) of IWP-2-V2, the cell expriment (test) of IWP-2-V2, the in vivo, in vitro and clinical trial test of IWP-2-V2, the EC50, IC50,and Affinity of IWP-2-V2, Please contact DC Chemicals..

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.