Y-320 is a potent inhibitor of the STING with IC50 of 356 nM, approximately 8-fold more potent than the canonical STING inhibitor tool drug H-151. Y-320 blocks STING Golgi translocation and downstream signaling and dose-dependently ameliorates cisplatin-induced acute kidney injury in mice.

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.