Description:
p-Cresol glucuronide is a metabolite of p-cresol, a uremic toxin formed by bacterial fermentation of proteins in the large intestine. It is formed from p-cresol primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A6, but also by UGT1A9, in huma
Handling:
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance,
we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one
month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at
least 1 hour.
Reference:
1. Rong, Y., and Kiang, T.K.L. Characterizations of human UDP-glucuronosyltransferase enzymes in the conjugation of p-cresol. Toxicol. Sci. 176(2), 285-296 (2020).
2. Gryp, T., De Paepe, K., Vanholder, R., et al. Gut microbiota generation of protein-boun