Mirvetuximab soravtansine Datasheet DC Chemicals
Description Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage.
Cat.No A1101
Name Mirvetuximab soravtansine

Chemical Properties

CAS 1453084-37-1
Synonyms Mirvetuximab soravtansine;huMov 19;IMGN853;IMGN 853;Mirvetuximab soravtansine [USAN];mirvetuximab-soravtansine;98DE7VN88D;Q27272114
pH value Corresponds to reference standard: PASS
Non-reduced CE-SDS >95%
SEC-HPLC >95%
Isoelectric Point Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality Corresponds to reference standard: PASS
Peptide mapping Corresponds to reference standard: PASS
N-terminal sequence Corresponds to reference standard: PASS

References

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